K. K. Pharma Solutions

Ilaris Interleukin – 1 beta inhibitors. DESCRIPTION AND COMPOSITION Pharmaceutical form Powder for solution for injection. The powder is a white lyophilisate. Active substance Each vial contains 150 mg of canakinumab (plus 30mg of canakinumab (20%) as overfill). Canakinumab is a recombinant fully human monoclonal antibody expressed in mouse myeloma Sp2/0 cell. Excipients Sucrose, L-Histidine, L-Histidine HCl monohydrate, Polysorbate 80. INDICATIONS Cryopyrin-Associated Periodic Syndromes (CAPS) Ilaris is indicated for the treatment of Cryopyrin-Associated Periodic Syndromes (CAPS), in adults and children aged 2 years and older including: • Familial Cold Autoinflammatory Syndrome (FCAS) /Familial Cold Urticaria (FCU), • Muckle-Wells Syndrome (MWS), • Neonatal-Onset Multisystem Inflammatory Disease (NOMID) / Chronic Infantile Neurological, Cutaneous, Articular Syndrome (CINCA). Systemic Juvenile Idiopathic Arthritis (SJIA) Ilaris is indicated for the treatment of active Systemic Juvenile Idiopathic Arthritis (SJIA) in patients aged 2 years and older who have responded inadequately to previous therapy with NSAIDS and systemic corticosteroids. Ilaris can be given as monotherapy or in combination with methotrexate.

SKYRIZI is a prescription medicine used to treat adults with:

• moderate to severe plaque psoriasis who may benefit from taking injections or pills (systemic therapy) or treatment using ultraviolet or UV light (phototherapy).
• active psoriatic arthritis.
• moderate to severe Crohn's disease.
• moderate to severe ulcerative colitis.

Uses of medication: Nusinersen is used for the treatment of spinal muscular atrophy (SMA) in the adult patient as well as in pediatric. This medication is a survival motor neuron-2 (SMN2) directed antisense oligonucleotide.Dosage: SPINRAZA (nusinersen) injection comes as the strength of 12 mg/5 mL (2.4 mg/mL). The recommended dose of spinraza should be administered intrathecally. This drug is given in four loading doses; the first three loading doses are given within 14 days; however, the 4th loading dose is given after the 30 days of the 3rd loading dose. The maintenance spinraza dose needs to be administered once every 4-months thereafter.Treatment Reactions: The most commonly reported nusinersen side effects may include constipation, upper respiratory infection and lower respiratory infection.Warnings and precautionsIn patients taking spinraza treatment, renal toxicity, including potentially fatal glomerulonephritis may occur.Excessive use of spinraza sma may lead to renal toxicity which can be spotted by urine protein testing.The nusinersen (spinraza) 12 mg/5 ml is not recommended during pregnancy or breastfeeding as it can affect the baby.Prior to each spinraza dose, patients should be monitored for the platelet count, activated partial thromboplastin time and quantitative spot urine protein testing.

Asklerol 3% Injection is a prescription medicine used in the treatment of varicose veins. It is a sclerosing agent that damages the layer of blood vessels, leading to platelet aggregation. This will lead to an occluded vessel and then it is finally replaced with connective tissue.

Asklerol 3% Injection is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are pain or discomfort in extremity, injection site swelling or pain, and superficial thrombophlebitis. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.

Targocid 400mg Injection is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (eg. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood, and others.

The semi-rigid vial is fabricated from a specially formulated polyolefin. It is a copolymer of ethylene and propylene.

Xylistin Forte 2MIU Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It is commonly used for critically ill patients admitted to the hospital.

Additional Information:

• Production Capacity: 36 months
• Delivery Time: within week

Xylistin 4.5MIU Injection is an antibiotic that works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections. This medicine is usually given as an injection by a doctor or nurse and should not be self-administered at home

Additional Information:

• Production Capacity: 36 months
• Delivery Time: within week

Novomix 30 100IU/ml Penfill is a combination of two medicines used to improve blood sugar control in people with type 1 and type 2 diabetes mellitus. It is a fast-acting type of insulin that helps to lower blood sugar levels after meals and reduce the chances of developing serious complications of diabetes.

Fulzos 250mg Injection is an estrogen blocker. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and slow down the growth of cancer cells.

Fulzos 250mg Injection is given as an injection into the muscles under the supervision of a doctor. It should be taken as doctor your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include injection site reaction, headache, vomiting, allergic reaction, and nausea. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you ever had kidney or liver disease or had bleeding disorder or had any blood clotting medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding.Side effects of Fulzos InjectionMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Fulzos

• Nausea
• Vomiting
• Back pain
• Fatigue
• Hot flashes
• Decreased appetite
• Constipation
• Bone pain
• Joint pain
• Cough
• Injection site pain
• Headache
• Pain in extremity
• Musculoskeletal (bone, muscle or joint) pain
• Breathlessness
• Increased alanine aminotransferase
• Increased aspartate aminotransferase
• Weakness

For the treatment of ovarian cancer, lung cancer (non-small ceSide effects

• Nausea, vomiting, diarrhoea, constipation
• Fatigue, loss of appetite, weakness
• Headache, dizziness, chills, fever, cough
• Pain in joints & muscles
• Skin rash, hair loss
• Sleep problems, weight loss
• Low blood platelets, anaemia, low WBCs

ll lung cancer), breast cancer

Tetanus Vaccine Adsorbed 0.5ml is used as a vaccination to prevent tetanus (also known as lockjaw). During childhood, four doses are recommended, with a fifth given during adolescence. Additional doses every 10 years are recommended.

Tetanus Vaccine Adsorbed 0.5ml is administered by a healthcare professional and should not be self-administered. It is important that the child receives all the vaccination doses. For the vaccine to be most effective, it is important to get the vaccination booster injection every 10 years.

Some of the common side effects of this medicine include reactions at the site of vaccination injection (such as pain, swelling, and redness), fever, and loss of appetite. If these side effects do not go away with time or get worse, let the doctor know. The doctor may help with ways to reduce or prevent these symptoms.

To make sure the vaccine is safe, before receiving the vaccine, it is important to let the doctor know if you have any other illnesses. You should also tell the doctor about all the medicines you are taking.

Rebopag 25mg Tablet is used to treat low platelet count due to chronic immune (idiopathic) thrombocytopenic purpura (ITP) or chronic hepatitis C virus (HCV) infection. It is also used to treat severe aplastic anemia.

Rebopag 25mg Tablet is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. The function of platelets is to help reduce bleeding.

Take it in the exact dose and duration as advised by the doctor. You may take it on an empty stomach. This medicine is to be swallowed as a whole. Do not chew, crush or break it. Inform your doctor if you have any known allergies to this medication.

The common side effects include nausea, vomiting, diarrhea, upper respiratory tract infection, and urinary tract infection. Let your doctor know if any of these side effects bother you. They may be able able to suggest ways to reduce or treat the symptoms.

Before you take this medicine, inform your doctor if you have any preexisting medical conditions. Let your doctor also know about all the other medicines you are taking. Dose adjustments may be required in patients with liver diseases, inform your doctor.

Ambilon 50mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections and leishmaniasis. It kills fungi by destroying the fungal cell membrane. This way it helps treat the condition.

Additional Information:

• Delivery Time: within week

Guficol Plus 1MIU Injection is an antibiotic that works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections. This medicine is usually given as an injection by a doctor or nurse and should not be self-administered at home.

Additional Information:

• Production Capacity: 36 months
• Delivery Time: within week

Ticofic Plus 400mg Injection is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (eg. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood, and others.

Additional Information:

• Production Capacity: 36 months
• Delivery Time: within week

Rybrevant 350mg injection contains the active substance Amivantamab. It is an antineoplastic drug that belongs to the class of medications called bispecific antibodies. It is used to treat a type of cancer called non-small cell lung cancer (NSCLC) that spreads to other parts of the body and has certain changes in a gene called EGFR. It is also used if it cannot be removed by surgery and has worsened during or after treatment with other anticancer medications.  

Do not take this injection if you are allergic to amivantamab or any other ingredients of this medicine. Inform your physician if you have suffered from inflammation of your lungs or any other lung conditions before initiating the therapy. Report to your physician if you face any symptoms of sudden difficulty in breathing, cough, or fever that may suggest inflammation of the lungs. Rybrevant 350mg injection is not recommended for children or young people below 18 years of age.  

Inform your physician if you have kidney problems, liver or lung problems before initiating the therapy. The common side effects of Rybrevant 350mg injection are rash, nail inflammation, musculoskeletal pain, shortness of breath, nausea, fatigue, swelling, inflamed and sore mouth, cough, constipation, and vomiting. This medicine may cause harm to the fetus hence use effective contraception during the treatment.

Uses of Rybrevant 350mg Injection

• Non-small cell lung cancer (NSCLC)

Therapeutic Effects of Rybrevant 350mg Injection

Rybrevant 350mg injection is an epidermal growth factor receptor (EGFR), and mesenchymal-epithelial transition factor (MET) targeted bispecific antibody that has been designed to recognize and attach to specific targets in the body. It targets two proteins found in cancer cells. It works by attaching to these proteins and may help to slow or stop your lung cancer from growing. It may also reduce the size of the tumor. 

Interaction of Rybrevant 350mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Rybrevant 350mg injection and reduce its effectiveness by causing undesirable side effects. 

More Information about Rybrevant 350mg Injection

• Store Rybrevant 350mg injection in the refrigerator (2°C to 8°C)
• Do not freeze
• keep the injection away from the reach of children and pets.
• If you have missed any dosing appointments, inform your doctor and schedule immediately.

Tecentriq Injection belongs to a group of medicines called monoclonal antibodies. It is used in the treatment of non-small cell lung cancer, small cell lung cancer, hepatocellular carcinoma, and melanoma.

Tecentriq Injection is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include fatigue, nausea, decreased appetite, constipation, cough, and shortness of breath. Some side effects such as chest pain, diarrhea, and dark urine might require immediate action. Inform your doctor if it bothers you, as there may be a way to prevent the side effects.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Velcade 1mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.

Velcade 1mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking Velcade 1mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem.  It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

LUMIgan 0.03% Ophthalmic Solution is a medicine used to reduce pressure in the eyes in adults with glaucoma and high pressure in the eye. If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood.

LUMIgan 0.03% Ophthalmic Solution is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. Make sure you remove contact lenses if you wear them and wait for at least 15 minutes before putting them back.

The most common side effects of this medicine include conjunctival hyperemia and eye itching. If you get any side effects, talk to your doctor. They may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short term side effect.Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

• Conjunctival hyperemia
• Eye itching

Victoza® is a noninsulin diabetes medication used along with diet and exercise to improve blood sugar in adults and children 10 years of age and older with type 2 diabetes. Victoza® starts to lower blood sugar levels in as soon as 2 weeks, lowers A1C, and keeps it down.

Additional Information:

• Production Capacity: 36 month
• Delivery Time: within week

Fludarabine Phosphate Injection USP 50 mg is indicated for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen.

Additional Information:

• Delivery Time: within week